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21 Aug
Austen Pleasants
OT
Status
QUESTIONABLE
Pleasants won't return to Thursday's preseason game at the Chargers due to a knee injury, Jennifer Lee Chan of NBC Sports Bay Area reports
Renardo Green
CB
Status
QUESTIONABLE
Green has a hamstring injury and is questionable to return to Thursday's preseason matchup with the Chargers.
George Kittle
TE
Status
PUP-P
Kittle (Achilles) visited with Dr. Neal ElAttrache on Wednesday and remains ahead of schedule in his recovery with a chance to play Week 1 against the Rams, Adam Schefter of ESPN reports.
Christian McCaffrey
RB
Status
QUESTIONABLE
McCaffrey (undisclosed) will not play in Thursday night's preseason game against the Chargers, David Lombardi of SFStandard.com reports.
Patrick Taylor Jr.
RB
Status
IR
The 49ers placed Taylor (undisclosed) on injured reserve Thursday, David Lombardi of SFStandard.com reports.
20 Aug
Titus Leo
DE
Status
IR
Leo (undisclosed) reverted from waivers to San Francisco's injured reserve list Wednesday, Nick Wagoner of ESPN.com reports.
19 Aug
Brett Toth
C
Status
QUESTIONABLE
Dominick Puni
G
Status
QUESTIONABLE
Gracen Halton
DT
Status
QUESTIONABLE
Nate Hobbs
CB
Status
QUESTIONABLE
Kyle Juszczyk
FB
Status
QUESTIONABLE
Luke Gifford
LB
Status
QUESTIONABLE
Mykel Williams
DE
Status
PUP-P
Coach Kyle Shanahan said Tuesday that Williams (knee) is considered a "long shot" to play in Week 1 against the Rams, Dylan Grausz of NBC Sports reports.
18 Aug
Nick Bosa
DE
Status
QUESTIONABLE
Bosa's (knee) tendinitis symptoms have been subsiding recently, David Lombardi of SFStandard.com reports.
Mike Evans
WR
Status
QUESTIONABLE
Kyle Shanahan said after Tuesday's joint practice with the Chargers that Evans experienced some quadriceps tightness, and the coach doesn't believe the issue is a serious one, Matt Maiocco of NBC Sports Bay Area reports.
14 Aug
Jordan James
RB
Status
QUESTIONABLE
James (ribs) will not play in Thursday's preseason opener against the Titans, Nick Wagoner of ESPN.com reports.
Christian Kirk
WR
Status
QUESTIONABLE
Kirk (calf) is not suited up for Thursday's preseason opener against the Titans, Nick Wagoner of ESPN.com reports.
13 Aug
Ricky Pearsall
WR
Status
IR
Pearsall announced Thursday in a post on his personal Instagram account that he underwent season-ending surgery to repair the PCL in his right knee, David Lombardi of SFStandard.com reports.
4 Aug
Mikail Kamara
DE
Status
IR
Kamara (knee) reverted to the 49ers' injured reserve Monday, per the NFL's transaction log.
1 Aug
Tanner McLachlan
TE
Status
IR
McLachlan (undisclosed) reverted to the 49ers' injured reserve Saturday, per the NFL's transaction log.
Keion White
DE
Status
QUESTIONABLE
White (groin) left Saturday's practice early, Nick Wagoner of ESPN.com reports.
31 Jul
Andrew Farmer II
DE
Status
IR
San Francisco placed Farmer (back) on its injured-reserve list Thursday, Aaron Wilson of KPRC 2 Houston reports.
29 Jul
Malik Mustapha
S
Status
QUESTIONABLE
Mustapha (hamstring) won't practice Wednesday, Matt Barrows of The Athletic reports.
28 Jul
Vederian Lowe
OT
Status
QUESTIONABLE
Lowe suffered a high ankle sprain during the 49ers' practice Sunday, Nick Wagoner of ESPN.com reports.
25 Jul
Isaac Guerendo
RB
Status
PUP-P
The 49ers placed Guerendo (pectoral) on the active/PUP list Saturday, Matt Maiocco of NBC Sports Bay Area reports.
