Jahlil Jenkins and Kaleb Bishop made successive layups to put the Knights up 50-47 with 9:55 remaining. But Moore sandwiched a layup and a 3-pointer between a Romeo Weems layup that started a 14-2 run and Fairleigh Dickinson never recovered.
The Blue Demons (3-0) played their third game in four nights. DePaul scored 19 points off 21 Fairleigh Dickinson (1-1) turnovers. Jaylen Butz added 13 points for DePaul.
Jenkins scored had 17 points for the Knights (1-1), and Elyjah Williams and Bishop each scored 12.
DePaul plays at Iowa on Monday and Fairleigh Dickinson travels to Fordham Wednesday.
For more AP college basketball coverage: https://apnews.com/Collegebasketball and http://twitter.com/AP-Top25
Elements of this story were generated by Automated Insights, http://www.automatedinsights.com/ap, using data from STATS LLC, https://www.stats.com
Balanced No. 5 Michigan hits road to face Illinois
The fifth-ranked Michigan basketball team doesn't have a go-to scorer. The Wolverines' starters take a committee approach on offense, and now the bench is increasing its production.
No. 15 Arizona looks for rebound game vs. Omaha
No. 15 Arizona, coming off its first loss of the season, will look to build on a positive defensive performance when it hosts Omaha on Wednesday night in Tucson, Ariz.
Umude's 21 points lead South Dakota past Alabama St.
— Stanley Umude scored 21 points on 9-of-13 shooting and South Dakota beat Alabama State 73-59 on Monday night.