Esteghlal emerged from a tough Group C on the final day of matches while Xavi's Al Sadd couldn't get enough help to advance.
Al Nassr booked their ticket with a win over Al Sadd, while three sides have a shot in Group C. Here's a look ahead of the final day of matches.
Stars like Bafetimbi Gomis and Omar Kharbin will need to turn up their play to salvage their teams' AFC Champions League campaign.
Tournament favorites and QSL champs Al Sadd SC find themselves at the bottom of their group and with just one point after two matches.
Tractor FC struck late to salvage a 3-3 draw against Pakhtakor Tashkent after all six goals were scored in the second half.
Ahead of the start of West Zone action in AFC Champions League 2021, we look at the five major talkings points from Asia's premier club competition.
A late header from Issa Alekasir was all the scoring Persepolis needed to advance to the West Zone quarterfinals.
The final day of play started with all four teams from Group C still vying for the last two spots in the knockout rounds.
Saudi Arabia's Al Nassr FC on Friday secured a place in the knockout stages of AFC Champions League after a 2-0 win against Sepahan SC.
Al Ain managed to grab their first point of the 2020 ACL season in a 3-3 tie against Group D contenders Al Sadd.
Santi Cazorla joining Al Sadd could cause a shift in the West Zone as numerous clubs look to unseat Al Hilal's reign at the top.
Barcelona great Xavi Hernandez has become the latest high profile sportsperson to test positive for coronavirus.
Former Arsenal and Villarreal midfielder Santi Cazorla will now play for Barca great Xavi at Al Sadd in the AFC Champions League.
One day after confirming he turned down an offer to coach Barcelona, Xavi led Al Sadd to Qatar Cup victory over Al Duhail.
A sensational goal from Argentine Leonel Vangioni helped reigning CONCACAF champion Monterrey set up a CWC clash with Liverpool.
Qatari champions Al Sadd converted a free kick given away with a back pass to the goalkeeper to set up a 3-1 extra-time win over Hienghene Sport.
Asia's reigning player of the year has been banned for five months for confronting a referee in the Asian Champions League semifinals.
Many in Spain have tipped Xavi Hernandez to follow in Pep Guardiola's footsteps and return to the Camp Nou as manager.
Madrid-born Gabi played 413 games for Atletico Madrid in two different spells, winning six trophies including the La Liga title.
Former Barcelona midfielder Xavi Hernandez has penned a new two-year deal with Al-Sadd to extend his stay in Qatar until at least 2020.