The injury to goalkeeper Francis Uzoho has come at a terrible time for the Super Eagles, as they head into a glut of Afcon and World Cup qualifiers.
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Joe Aribo and Semi Ajayi aren't supposed to be starters for Nigeria, but excellent efforts in recent weeks have complicated matters for their coach.
Neymar went off injured 12 minutes into Brazil's 1-1 draw with Nigeria in a friendly in Singapore on Sunday.
With the Super Eagles team settled, for the most part, Nigerian fans will be focused on Gernot Rohr's coaching and game plan vs. Brazil.
Results and performances in Senegal suggest that NPFL players are nowhere near good enough to be playing international football for Nigeria.
Nigeria's Super Eagles crashed out of the 2019 WAFU Cup of Nations after a disastrous penalty shoot-out saw them lose 3-2 to Cape Verde.
Nigeria's defeat to Togo at the WAFU Cup of Nations saw them drop to the Plate competition, where they must beat Cape Verde to salvage any goodwill.
Promise Isaac, who captained Nigeria to the 2008 Olympic silver medal and scored 79 goals in 11 professional seasons in Turkey, has died.
"The quality of players we had in the team then [was such that] everyone believed that each one of us would play in the senior national team."
Must be something in the new season air. Or could it just be early season ginger? Whatever, Nigerian players carried their good form into September.
Mfon Sunday Udoh must have thought Halloween had come early, given his nightmare performance in Nigeria's opening 2019 WAFU Cup of Nations match.
Nigeria have lost twice in seven days to Togo after going down 2-1 in the third match of the 2019 WAFU Cup of Nations on Sunday.
Nigeria's latest squad call-up once again brought disappointment for admirers of QPR's Ebere Eze, despite rumours of Premier League interest.
Nigeria coach Gernot Rohr is infamous for his lack of faith in the Nigerian domestic league, but the WAFU Cup of Nations could change his mind.
Senegal, the hosts, have won the WAFU Cup of Nations, while Guinea have claimed the Plate title.
Who will follow Nigeria, Togo and Ghana into the record books as WAFU Cup of Nations champions?
Ahead of the WAFU Cup of Nations that kicks-off this weekend, ESPN's Ed Dove asks what became of some of the stars of previous tournaments.
Nigeria have been to the final at each of the three WAFU Cup of Nations they have contested, winning once. Who was their best player?
Arguably the best Nigerian transfer of the offseason was the one that happened just before the European deadline, and went almost unnoticed.
Imama Amapakabo, who will coach Nigeria at the WAFU Cup of Nations in Senegal, tells ESPN that his objectives are broader than winning.
Chelsea striker Tammy Abraham has refused to rule out the possibility of playing for Nigeria despite earning two international caps for England.
Striker Chidera Ejuke is an unknown quantity to Nigeria fans, but he hopes a win for Heerenveen against Ajax Amsterdam will get his name in lights.
Gernot Rohr's refreshed team buzz their way close to embarrassing Ukraine, but it was Rangers' Joe Aribo who shone the brightest. Mikel shmikel...