CFR Cluj-Napoca CLUJ 3 - 1 |  KuPS Kuopio KUPS | FT | Stadionul Dr. Constantin Radulescu | N/A |
Ararat-Armenia ARA 1 - 2 |  Red Star Belgrade RSB | FT | GSP Stadium | N/A |
Dinamo Zagreb ZAG 3 - 1 |  Flora FLO | FT | Maksimir | N/A |
Liberec LIB 1 - 0 |  Apoel Nicosia APO | FT | U Nisy, Czech Republic | N/A |
Malmo FF MAL 1 - 3 |  Granada GCF | FT | Eleda Stadion | N/A |
Rosenborg ROS 0 - 2 |  PSV Eindhoven PSV | FT | Lerkendal Stadium | N/A |
Royal Charleroi SC CHA 1 - 2 |  Lech Poznan LECH | FT | Stade du Pays de Charleroi, Belgium | N/A |
Hapoel Be'er HAPO 1 - 0 |  Viktoria Plzen PLZ | FT | Ha Moshava | N/A |
Dinamo Brest BRE 0 - 2 |  Ludogorets Razgrad LUDO | FT | Dinamo Stadion, Minsk | N/A |
FC Copenhagen COP 0 - 1 |  Rijeka RIJE | FT | Telia Parken, Gelsenkirchen | N/A |
FK Sarajevo FKSA 0 - 1 |  Celtic CEL | FT | Bilino Polje | N/A |
Legia Warsaw LEGI 0 - 3 |  FK Qarabag FKQA | FT | Polish Army Stadium | N/A |
Standard Liege STL 3 - 1 |  Fehérvár FEH | FT | Stade Maurice Dufrasne | N/A |
Dundalk DUND 3 - 1 |  KI Klaksvik KLA | FT | Aviva Stadium | N/A |
FC Basel BAS 1 - 3 |  CSKA Sofia CSKA | FT | St. Jakob-Park | N/A |
Young Boys BOY 3 - 0 |  SK Tirana SK Tirana | FT | Wankdorf | N/A |
AEK Athens AEK 2 - 1 |  VfL Wolfsburg WOLF | FT | Athens Olympic Stadium | N/A |
Rangers RAN 2 - 1 |  Galatasaray GAL | FT | Ibrox Stadium, Scotland | N/A |
Rio Ave RIO 2 - 2 |  AC Milan MIL | FT-Pens | Estádio do Rio Ave | N/A |
| AC Milan win 9-8 on penalties |
Sporting CP SCP 1 - 4 |  LASK Linz LAS | FT | Estádio José Alvalade | N/A |
Tottenham Hotspur TOT 7 - 2 |  Maccabi Haifa HAI | FT | Tottenham Hotspur Stadium | N/A |