Wyoming (2-2) struggled on offense until Vander Waal caught fire in the fourth quarter, completing 11 of 17 passes for 133 yards.
But the Terriers gained only one first down and punted, setting up the Cowboys' game-winning drive with 1:59 remaining. On the game-winner, Ismail sliced right to left across the middle, taking Vander Waal's toss at the 5, eluding a tackle by Rountree and diving into the front left corner of the end zone.
Wofford's Joe Newman, who was 9 of 15 for 73 yards passing with two interceptions, faked a handoff up the middle then raced around right end untouched for a 4-yard TD that put the Terriers up 14-10 with 13:06 remaining.
Andre Stoddard's punishing 4-yard TD run had given Wofford a 7-3 lead in the second quarter but Vander Waal split two defenders with a 6-yard strike over the middle to Tyree Mayfield, leaving the Cowboys ahead 10-7 at the half. It was Vander Waal's first scoring toss of the season and his career. His second, to the son of former NFL and college star Raghib "Rocket" Ismail, allowed the QB to finish with a career-best 224 yards. He completed 25 of 42 passes with one interception.
Wofford's Lennox McAfee led all rushers with 91 yards on 13 attempts. Andre Stoaddard added 61 yards on 17 carries.
Wofford: After a school-best 671 yards last week against VMI, the Terriers were hoping their offense would shine again against a Wyoming defense that was shredded the previous two weeks. For most of the game, it was the defense that rose to the occasion. The last drive soured an otherwise outstanding effort and Wofford fell to 1-20 against FBS competition.
Wyoming: Playing their final non-conference game, the Cowboys needed a confidence boost after two blowout losses to Power 5 teams. A loss to an FCS team would have been devastating. Wyoming still has plenty of questions on offense, but the defense was much improved, and Vander Waal looked very confident on the final two drives.
Wofford: The Terriers take next weekend off before their final pre-Southern Conference tuneup, Sept. 29 at Gardner-Webb.
Wyoming: After a bye week, the Cowboys open Mountain West play by hosting Boise State Sept. 29. The Broncos are the defending Mountain Division champions, and the two teams shared the title in 2016 with New Mexico.
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