Biggest Week 12 injury questions for all 32 NFL teams: Uncertainty surrounds Nick Foles, 49ers running backs

There could be more changes coming at the NFL's most important position.

Quarterback Nick Foles missed Wednesday's practice because of a hip injury, and Mitchell Trubisky -- who just returned himself from a shoulder injury -- took all the reps.

But the injury news wasn't all negative. Niners running back Raheem Mostert participated in Wednesday's practice. The Chiefs could be on track to get WR Sammy Watkins back in time to face the Buccaneers. Running back Christian McCaffrey returned to practice Wednesday for the first time since suffering a shoulder injury three weeks ago -- but he's not expected to play Sunday at Minnesota. And the Eagles could get a boost in the NFC East race with the possible return of TE Zach Ertz, who is "trending in the right direction" according to coach Doug Pederson.

Here's a roundup of the biggest injury situations from ESPN's NFL Nation reporters:

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Buffalo Bills

What is going on with Mitch Morse? He cleared concussion protocol in Week 10 and was active for the Bills' game against the Cardinals but did not play. Sean McDermott called it a football decision, which seems odd considering Buffalo made Morse the league's highest paid center at the time it signed him last offseason. If he's healthy enough to play and Cody Ford returns to the lineup, the Bills will have their full starting five offensive line for the first time all season. -- Marcel Louis-Jacques

Miami Dolphins

The Dolphins running backs room is a question once again with lead back Salvon Ahmed nursing a shoulder injury that forced him to miss practice Wednesday. Meanwhile, Myles Gaskin was designated to return off IR and practiced in a red non-contact jersey Wednesday as he rebounds from a knee sprain. Coach Brian Flores was noncommittal on Gaskin's status for Sunday. So the Dolphins might have one, both or neither. If it's the latter, Matt Breida, Patrick Laird and DeAndre Washington would carry the load. -- Cameron Wolfe

New England Patriots

Starting left tackle Isaiah Wynn has a knee injury that knocked him out of the final two plays of Sunday's loss to the Texans, and he hasn't practiced this week, which seems to foreshadow that the Patriots will have to go to Plan B. The question then becomes if that's veteran Jermaine Eluemunor or rookie Justin Herron. -- Mike Reiss

New York Jets

QB Sam Darnold, sidelined the past two games because of a shoulder injury, is trending toward a return to the lineup Sunday. He took all the first-team reps Wednesday, a clear indication the plan is to start him against the Dolphins. The Jets will wait until the end of the week to make it official, just in case there's a setback. If he's cleared, Darnold will get his first chance to play with the three starting wide receivers. -- Rich Cimini


Baltimore Ravens

One of the largest COVID-19 outbreaks in the league this season has cast doubt over the entire roster. In the past three days, the Ravens have put seven players on the reserve/COVID-19 list who have totaled 2,127 snaps this season. This includes two running backs (J.K. Dobbins and Mark Ingram), their sacks leader (defensive end Calais Campbell) and their top two centers (Patrick Mekari and Matt Skura). -- Jamison Hensley

Cincinnati Bengals

The status for the Bengals' top running back is in question yet again. This time it's Giovani Bernard, who missed Wednesday's practice because of a concussion. Bernard didn't play in the Bengals' final two offensive drives against Washington, according to NFL Next Gen. Bernard was the last Cincinnati running back who was capable of being a serviceable fantasy option. Even if he didn't participate at practice, Bernard was present for the portion open to the media. It'll be a situation worth watching the rest of the week. -- Ben Baby

Cleveland Browns

The Browns will be without CB Denzel Ward, who suffered a calf injury, and could miss multiple games, according to the team. Ward, a Pro Bowler as a rookie in 2018, was playing like a Pro Bowl corner again this season. Cleveland's options to replace him include preseason waiver pickup M.J. Stewart, nickelback Kevin Johnson, special-teams ace Tavierre Thomas, undrafted rookie A.J. Green or reserve Robert Jackson. -- Jake Trotter

Pittsburgh Steelers

The postponement of the Steelers-Ravens game to Sunday might work to the Steelers' advantage -- at least injury-wise. JuJu Smith-Schuster and Joe Haden, both injured against the Jaguars, practiced Wednesday. Smith-Schuster (foot) was a full participant, and Haden (knee) returned as a limited participant. Barring any setbacks, both are trending toward playing with the extra rest. -- Brooke Pryor


Houston Texans

After missing Sunday's game against the Patriots because of an illness, left tackle Laremy Tunsil was listed as a full participant in practice two days in a row. Tackle Roderick Johnson played well in place of Tunsil in Week 11, but the Texans will be happy to have their Pro Bowl left tackle back. -- Sarah Barshop

Indianapolis Colts

The Colts have a number of concerns, especially on defense where defensive linemen DeForest Buckner and Denico Autry are both on the reserve/COVID-19 list. But quarterback Philip Rivers did not practice Wednesday due to a toe injury suffered while attempting to make a block in their Week 11 victory over Green Bay. The Colts are taking a cautious approach with Rivers and his toe to ensure he's ready for Sunday's game against Tennessee. -- Mike Wells

Jacksonville Jaguars

QB Mike Glennon is making his first start since Week 4 of the 2017 season and the health status of three of the Jaguars' top four wide receivers is uncertain. DJ Chark Jr. (ribs) and Chris Conley (hip) did not practice on Wednesday and Laviska Shenault Jr. (hamstring) was limited. Shenault has missed the past two games so him being on the practice field is positive but not having Chark, the team's best receiver, would be hard to overcome against Cleveland. -- Mike DiRocco

Tennessee Titans

Adoree' Jackson missed practice again because of a knee injury. He has yet to participate in a game or practice since being added to the active roster. Jackson is usually the corner the Titans match up with the Colts' T.Y. Hilton. That probably won't be the case this week and there's no telling when Jackson will return to the field. -- Turron Davenport


Denver Broncos

CB Bryce Callahan (foot) did not practice Wednesday and his status will bear watching through the week. Callahan did some work with the team's strength and conditioning coaches on a side field during Wednesday's practice. He has been at his best in recent weeks, including a game-saving interception against the Chargers. The Broncos face the Saints on Sunday, and while New Orleans WR Michael Thomas had played in only four games this season, he is coming off his first 100-yard effort this past week with 104 yards against the Falcons. -- Jeff Legwold

Kansas City Chiefs

Sammy Watkins appears to be on track to play for the first time since Week 5 on Sunday against the Bucs. He was a full practice participant Wednesday. Watkins has calf and hamstring injuries. The Chiefs would gladly take Watkins back in their lineup. Their depth at wide receiver has been diminished recently because of injuries. -- Adam Teicher

Las Vegas Raiders

Rookie cornerbacks Damon Arnette, a starter, and Amik Robertson, a backup in the slot, both missed practice Wednesday because of illnesses. Raiders coach Jon Gruden lamented his young secondary rarely practicing together this season due to injury and COVID-19 issues. And now, the Raiders face the No. 2-ranked passing offense in the NFL in the Falcons with DB Lamarcus Joyner still on the reserve/COVID-19 list. Ouch. -- Paul Gutierrez

Los Angeles Chargers

LB Uchenna Nwosu is out due to a shoulder (AC joint) injury for Week 12 at Buffalo. It's a Grade 2 sprain according to a report, but he's a big part of the defense and could go on IR. DE Jessie Lemonier is expected to replace him. Nwosu had 3½ sacks for the season -- Shelley Smith


Dallas Cowboys

Cornerback Anthony Brown is questionable for Thursday's game because of an aggravated rib injury that kept him out earlier in the season. Already without rookie Trevon Diggs (foot), the Cowboys called up Rashard Robinson and Deante Burton from the practice squad. Robinson was forced into action last week vs. Minnesota and could play a larger role Thursday, which is not a good thing if Terry McLaurin, who is questionable because of a foot injury, can play at full speed for Washington. -- Todd Archer

New York Giants

Second-round pick Xavier McKinney (foot) had his practice window opened earlier this week after being on injured reserve since the start of the season. The versatile safety practiced Wednesday in pads for the first time since surgery in the summer. McKinney seemed to be moving well but still seems unlikely to play Sunday against Cincinnati. The Giants need to get him back into playing shape first. -- Jordan Raanan

Philadelphia Eagles

Coach Doug Pederson said tight end Zach Ertz is "trending in the right direction" when asked about his status for Monday night's game against the Seahawks. Ertz has been sidelined since Week 6 because of a high ankle sprain but has practiced the past two weeks. If he gets through this week without incident, he could be back in the lineup vs. Seattle. -- Tim McManus

Washington Football Team

Receiver Terry McLaurin is questionable for Thursday's game at Dallas because of an ankle injury, but the good news for Washington is that he was able to participate in practice Tuesday. And, though it was only a walk-through, he was listed as a full participant Wednesday. It's hard to imagine him not playing vs. Dallas. Washington will be minus safety Deshazor Everett, who was ruled out for Thursday because of an ankle injury. He was going through drills Tuesday, a good sign for a Week 12 matchup at Pittsburgh. -- John Keim


Chicago Bears

The Bears seem on the cusp of making another quarterback change after Nick Foles (hip) missed practice Wednesday. Mitchell Trubisky, who just returned from a shoulder injury, took all the reps in practice and is the favorite to start versus the Green Bay Packers on Sunday night. Bears coach Matt Nagy is officially calling Foles "day-to-day" but Nagy expressed confidence in Trubisky, whom he benched in favor of Foles in Week 3. "I have all the confidence in the world in Trubisky if he has to start," Nagy said. "I'm impressed with how Mitch has grown week-to-week." -- Jeff Dickerson

Detroit Lions

Who will play corner and receiver? The Lions again ruled Kenny Golladay (hip) and Danny Amendola (hip) out, so Marvin Hall and Mohamed Sanu Sr. could have larger Thanksgiving roles. At corner, Amani Oruwariye (back) is questionable, and both Jeff Okudah (shoulder) and Mike Ford (concussion) are out. So it's potentially a thin group with Desmond Trufant, Justin Coleman and practice squad call-up Dee Virgin the healthy options if Oruwariye can't go -- with safety C.J. Moore or converted corner Jamal Agnew in a pinch. -- Michael Rothstein

Green Bay Packers

You might not think a center is the most important injury -- especially for a team with nearly 20 players on their medical report, but Corey Linsley's back injury is cause for concern. Yes, the Packers adapted when Linsley dropped out against the Colts, but the seventh-year pro plays a critical role in the pre-snap adjustments that the Packers and Aaron Rodgers make at the line of scrimmage. Linsley warmed up with the team Wednesday but stayed inside when the rest of the players went outside for drills during the open portion of practice. He was officially listed as a limited participant. -- Rob Demovsky

Minnesota Vikings

Adam Thielen remains quarantined on the reserve/COVID-19 list. It's unknown whether the Pro Bowl receiver tested positive, which would keep him out of Sunday's game against Carolina, or if he was a close contact with someone who has the virus and could be activated in time for Week 12 should he continually test negative this week. In his absence, Irv Smith Jr. could see a spike in targets the way he did the last time Thielen missed time in 2019, but the second-year tight end was limited Wednesday because of a groin/back injury. -- Courtney Cronin


Atlanta Falcons

Almost all of the Falcons' skill position players are injury questions early in the week. Julio Jones practiced on a limited basis Wednesday because of the hamstring injury that sidelined him for much of last week's game at New Orleans. Calvin Ridley (foot) also practiced on a limited basis. But RB Todd Gurley II (knee) and TE Hayden Hurst (ankle) did not practice. The severity of Gurley's injury is unknown, but it's worth monitoring since he did not play in the fourth quarter of Sunday's loss. -- Mike Triplett

Carolina Panthers

Running back Christian McCaffrey returned to practice Wednesday for the first time since suffering a shoulder injury three weeks ago, but he is not expected to play Sunday at Minnesota. It appears McCaffrey won't return until after the bye week for a Dec. 13 game against Denver. Mike Davis will once again handle the bulk of the running back duties. -- David Newton

New Orleans Saints

Top CB Marshon Lattimore was back to full practice participation Wednesday -- a good sign that he should be able to return from the abdomen injury that sidelined him last week. That's good news against a Denver offense that features multiple WR threats in Jerry Jeudy and Tim Patrick. RB Alvin Kamara (foot) and WR Michael Thomas (ankle) were limited in Wednesday's practice, but they have been playing through those injuries. -- Mike Triplett

Tampa Bay Buccaneers

Starting cornerback Jamel Dean left the Rams game and is now in the concussion protocol -- not at all ideal when preparing to face the No. 1 passing team in the league in Kansas City. Ross Cockrell filled in as the third cornerback. Backup center A.Q. Shipley, who started the past two weeks, suffered a neck injury on the final drive against the Rams and did not practice Wednesday, but left guard Ali Marpet was a full participant after missing the past three games because of a concussion. He was still experiencing symptoms last week after he tried practicing in full on Thursday, so they're hoping for a better outcome this time. -- Jenna Laine


Arizona Cardinals

Kyler Murray was limited Wednesday as the Cardinals ease him along this week due to his injured right shoulder. Coach Kliff Kingsbury said the idea of having three quarterbacks active for Sunday's game at New England was discussed. Murray has tried to limit his throwing during the week in an effort to rest his shoulder. -- Josh Weinfuss

Los Angeles Rams

Linebacker Micah Kiser has a knee injury and Rams coach Sean McVay says he'll be "very surprised" if he's able to play Sunday against the 49ers. If Kiser is unable to go, Troy Reeder will start in his position alongside Kenny Young. Tight end Tyler Higbee has an elbow injury and his status is also uncertain for Sunday. Johnny Mundt could play an increased role if Higbee is sidelined. -- Lindsey Thiry

San Francisco 49ers

Running back Raheem Mostert (high ankle sprain) had his 21-day window to be activated from injured reserve opened on Tuesday and participated in Wednesday's practice. Since he's still on injured reserve, he didn't get an official injury designation Wednesday but coach Kyle Shanahan remains hopeful that Mostert will return Sunday against the Rams. Fellow running backs Jeff Wilson Jr. (ankle) and Tevin Coleman (knee) also could return this week, but the Niners often go as Mostert does. With that Rams defense next up, they need him more than ever. -- Nick Wagoner

Seattle Seahawks

Pete Carroll has said he expected running back Chris Carson to return this week along with cornerback Shaquill Griffin and center Ethan Pocic. That leaves right tackle Brandon Shell as the Seahawks' biggest question. Carroll said he'll be a close call for Monday night's game at Philadelphia because of the high-ankle sprain he suffered last week against Arizona. The Seahawks list Cedric Ogbuehi as their backup at both tackle spots, but they also have Jamarco Jones capable of stepping in on the right side. -- Brady Henderson