The return of the two players wasn't enough to boost the Cavaliers, who retained the NBA's worst record (8-30) after Wednesday night's 117-92 loss to the Miami Heat.
Thompson missed the past 10 games because of a sprained left foot. The 6-foot-10 forward is averaging a team-high 11.6 rebounds and is scoring 12 points a game.
Hood missed four games with a sore left Achilles tendon. He is averaging 12 points.
Cleveland coach Larry Drew said forward Kevin Love, who had surgery on his left foot in November, will visit a doctor soon as he continues to rehab his injury. Drew said Love has begun shooting drills but hasn't practiced. Love is expected to return this month.
Information from The Associated Press was used in this report.