Alexandru Mitrita scored twice, including the quickest goal in club history, helping New York City FC to a 4-0 victory over FC Cincinnati.
Maynor Figueroa scored in the 89th minute to lift the visiting Houston Dynamo to a 1-1 draw with the expansion Nashville SC on Saturday.
USL Championship side LA Galaxy II released defender Omar Ontiveros in the wake of an on-field racist incident involving the player.
Colorado Rapids' Major League Soccer clash with Sporting Kansas City originally scheduled for Sunday has been postponed.
MLS has notified several CONMEBOL federations that it will refuse to allow players to travel to upcoming World Cup qualifers, a source told ESPN.
Tori Penso, who became the first woman MLS referee since 2000, is hopeful to get more opportunities and games.
Playing for Dabo Swinney is an offer most can't refuse, but Tanner Tessmann did just that, and the Clemson coach's godson is thriving for FC Dallas.
Why FC Cincinnati, Hoffenheim are partnering: Player development, data sharing in pursuit of common goals
FC Cincinnati and TSG Hoffenheim's partnership aims to help both clubs improve both their scouting and give young players more opportunities.
Mexico coach Gerardo "Tata" Martino has talked to LA Galaxy duo Julian Araujo and Efrain Alvarez recently about playing for El Tri over the USMNT.
Bradley Wright-Phillips scored twice in the first 11 minutes as Los Angeles FC rolled to a 6-0 win over the visiting Vancouver Whitecaps on Wednesda
Yimmi Chara scored in a third consecutive match and Steve Clark made six saves as the Portland Timbers defeated the visiting Seattle Sounders 1-0.
Albert Rusnak scored one goal and assisted on another in the second half to lead Real Salt Lake to a 2-0 victory over the Los Angeles Galaxy.
Daniel Rios scored in the 70th minute as Nashville SC did just enough with a man advantage to earn a 1-0 victory over visiting DC United.
Cole Bassett had a goal and an assist, and the Colorado Rapids had four second-half goals for a 5-0 thrashing of fading San Jose.
FC Cincinnati's penchant for cooking up scoreless draws at home continued Wednesday when they played to a 0-0 tie against the Philadelphia Union.
Brian White scored the go-ahead goal in the 49th minute to lift the New York Red Bulls to a 4-1 victory over Inter Miami on Wednesday.
Orlando City struck for a pair of first-half goals and hung on to extend their unbeaten run to a club-record seven matches with a win over SKC.
|Columbus Crew SC||13||9||3||1||+17||30|
|Orlando City SC||13||7||4||2||+10||25|
|New York City FC||14||6||2||6||+4||20|
|New England Revolution||13||4||6||3||+1||18|
|New York Red Bulls||13||5||2||6||-2||17|
|Atlanta United FC||13||4||2||7||-4||14|
|Chicago Fire FC||13||3||3||7||-6||12|
|Inter Miami CF||13||3||2||8||-7||11|
|Seattle Sounders FC||12||6||3||3||+15||21|
|Sporting Kansas City||13||6||2||5||+4||20|
|Minnesota United FC||13||5||3||5||+3||18|
|Real Salt Lake||13||4||5||4||-2||17|
|San Jose Earthquakes||13||2||5||6||-21||11|