AS Roma ended a run of three successive Serie A defeats with a 2-1 win over Parma, who were angered after having a penalty turned down late.
Atalanta continued their remarkable season by beating Sampdoria 2-0 on Wednesday to extend their winning run to nine Serie A games.
Hakan Calhanoglu finds himself thrust into a veteran role as a young AC Milan side tries to get back to the top.
Fiorentina and Cagliari served up one of the dullest games since the Serie A season restarted just under one month ago when they played a draw.
A second-half goal from Hirving Lozano gave Napoli a 2-1 win at struggling Genoa in Serie A on Wednesday.
AC Milan's Hakan Calhanoglu said recent their recent run of wins shows that the Rossoneri belong among Serie A's top sides.
Patric bit Donati's arm in stoppage time and received a red card with Lecce 2-1 ahead against title-hopefuls Lazio.
With a combined age of 73 and 1,272 career goals between them, Cristiano Ronaldo and Zlatan Ibrahimovic may have met on the pitch for the last time.
Zlatan Ibrahimovic jokingly claimed that he runs AC Milan and danced around questions about his playing future after Tuesday's 4-2 win over Juve.
AC Milan scored three times in five astonishing second-half minutes as they hit back from two goals down to beat visiting Serie A leaders Juventus.
Lazio's fading Serie A title challenge suffered a potentially fatal blow when they lost 2-1 at relegation-threatened Lecce.