Kansas City Chiefs kicker Cairo Santos had as many field goals (five) and Manning had completions. Manning, who was struggling with foot and rib injuries, completed 5-of-20 passes for 35 yards with four interceptions.
With just over six minutes left in the third quarter Sunday, the Broncos benched Manning and put in Brock Osweiler.
For his part, Santos hit field goals on 33, 34, 48, 49 and 50 yards. He did miss a 48-yarder late in the game. Santos has 21 field goals this season.