England will be without captain Dylan Hartley on their tour of South Africa this June as he continues his recovery from concussion.
Northampton Saints' Wallabies centre Rob Horne has been forced into retirement just seven days after suffering nerve damage to his right arm.
Northampton lock Christian Day will retire from professional rugby at the end of this season.
England could face South Africa in June without captain Dylan Hartley as the Northampton hooker continues to suffer concussion symptoms.
Captain Rob Horne remains in hospital after suffering an arm injury during Northampton's win at Leicester on Saturday.
Dylan Hartley continues to be sidelined by concussion after the England captain was once again ruled out of club duty for Northampton.
Global insurance brokers Gallagher have been confirmed as new title sponsors of English rugby union's Premiership.
Dylan Hartley faces a race against time to be fit for England's tour to South Africa after Northampton Saints expressed concern over his latest concussion.
Saracens bounced back from their Champions Cup exit with a crushing 63-13 victory against Northampton Saints at Franklin's Gardens.
Northampton Saints fly-half Stephen Myler will leave the club at the end of the season.
George North has been "disciplined internally" by Northampton after he accepted responsibility for missing a training session ahead of his club's game against Sale earlier this month.
Dylan Hartley and Elliot Daly have emerged as doubts for England's clash with Ireland just hours after being cleared to start the final round of the Six Nations.
Northampton number eight Teimana Harrison's sending off proved pivotal as Bath booked their place in the final of the Anglo-Welsh Cup.
Warren Gatland says Welsh rugby will "look after" George North if his Northampton career ends early.
Joe Simmonds converted Thomas Waldrom's last-minute try to cap a dramatic comeback for Exeter, who rallied from 13 points down to edge out Northampton 31-30 at Sandy Park in the Aviva Premiership.
George North sent Wales coach Warren Gatland a timely reminder by sparking a superb second-half fightback to earn Northampton a 25-17 win against London Irish.
Kieran Brookes will leave Northampton Saints at the end of the season, the Aviva Premiership outfit have confirmed.
The winger, who tops 125kg, will leave Super Rugby team New South Wales Waratahs later this year, and will arrive at Saints in time to play alongside former Tahs teammate Rob Horne for the 2018-19 Aviva Premiership campaign.
The kicking of fly-half Freddie Burns guided Bath to a 32-9 Aviva Premiership win over Northampton at the Recreation Ground.
Hurricanes coach Chris Boyd has agreed to take over at Northampton Saints ahead of the 2018-19 Aviva Premiership season.
Northampton interim head coach Alan Dickens says George North's withdrawal before his side's 24-20 win over Sale in the Anglo-Welsh Cup was "a precautionary measure".
Nafi Tuitavake scored in the last minute to put Northampton in pole position to qualify from Pool 3 of the Anglo-Welsh Cup following a 24-20 triumph over Sale at the AJ Bell Stadium.