Danny Care will become England's most-capped scrum-half on Saturday after Eddie Jones made two changes to his starting XV for the Six Nations clash with Wales.
Care starts at scrum-half in the absence of Ben Youngs, who suffered a season-ending knee injury last weekend, and will earn his 78th cap -- overtaking Matt Dawson in the process.
Richard Wigglesworth takes Care's 'finisher' spot on the England bench and looks set to make his first appearance for his country since the 2015 Rugby World Cup.
The other change to the starting lineup sees Jonathan Joseph reclaim the No. 13 jersey from Ben Te'o, following England's convincing seven-try win over Italy in Rome.
"Danny Care very much deserves the honour of being the most capped England scrum-half and I am sure he'll make the most of his opportunity on Saturday," Jones said.
"The team is hugely excited about playing in front of 82,000 fans at Twickenham and we'll be well prepared and ready to go out there and beat Wales on Saturday.
"We want to make sure our set piece is dominant, our defence is ferocious and that we are at our best against Wales this weekend."
England squad to face Wales:
Brown, Watson, Joseph, Farrell, May, Ford, Care; Vunipola, Hartley (captain), Cole, Launchbury, Itoje, Lawes, Robshaw, Simmonds.
Replacements: George, Hepburn, Williams, Kruis, Underhill, Wigglesworth, Te'o, Nowell.