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Denny Solomona in line to start England's Six Nations opener

Denny Solomona has not appeared for England since being sent home from a training camp in August last year. Aitor Alcalde/Getty Images

Denny Solomona could win just his third England cap against Italy next month as injuries continue to disrupt Eddie Jones' plans for the Six Nations.

Solomona has not played for England since being sent home from a training camp alongside Manu Tuilagi in August for what the RFU described as "team culture issues", but the Sale Sharks star is in the squad for the upcoming Six Nations.

With Mike Brown "borderline" to face Italy in Rome, Jones has a problem to solve. Elliot Daly, Jack Nowell and Semesa Rokoduguni are all set to miss part or the entirety of the competition, which could clear the path for the rugby league convert.

In recent days in training, England have practised with a back three of Solomona, Jonny May and Anthony Watson -- with the latter moving to fullback to allow the New Zealand-born winger in.

Nathan Earle, who confirmed he would be leaving Saracens for a Harlequins earlier this week, forms Solomona's stiffest competition for a spot in Jones' XV in Rome on Feb. 4, should Brown be declared unfit.

Injuries are causing problems throughout Europe with every team in the Six Nations blighted, and England, who could be without 18 players -- either on the treatment table or suspended -- for the Italy game, are among the worst hit.

In addition to Daly, Nowell and Rokoduguni, Chris Robshaw is a major doubt for the trip to Rome, while Maro Itoje is facing a race against time to be fit for the opener, although the Saracens man is expected to be available.

Information from Press Association Sport was used in this report.