Leicester Tigers and England are waiting on the severity of the knee injury Ed Slater picked up in the first-half of Saturday's match against Saracens.
Slater, who is uncapped at Test level but skippered England's midweek side against the Crusaders in 2014, limped off after 29 minutes at Allianz Park after sustaining an injury to his knee.
"Ed tweaked his knee and it's not great," Leicester boss Richard Cockerill said post-match. "He certainly won't be fit for next week. He got whacked on the side and he tweaked his medial ligaments."
Slater is well versed in leg injuries having had an operation on his left knee 18 months ago but has impressed for the Tigers this term playing in both the back-row and in the locks.
His form led to Tigers coach Cockerill saying he should be in the England mix and the national side's new forwards coach Steve Borthwick was present at Saracens to assess contenders ahead of January 13 when Eddie Jones is set to unveil his first Elite Player Squad.
England currently have Henry Slade, Kieran Brookes, Jonny May, Dave Ewers, Alex Corbisiero and Manu Tuilagi on the sidelines.