Texas Southern (1-13) won its first game of the season in a Southwestern Athletic Conference opener for both teams.
Bruce made a career-best eight 3s on 12 attempts and Jefferson was 5 of 11 as Texas Southern made 15 of 38 from 3-point range. Jefferson reached 20-plus points for the 10th time this season.
Texas Southern went on a 17-5 run -- with three 3-pointers from Bruce -- midway through the first half for a 27-13 lead. But Southern closed the half by scoring the final six points to pull within 37-34.
Southern was within 52-48 with 13:37 to go but didn't make its next field goal until the 8:21 mark and trailed 66-51.
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Hot-shooting Villanova beats Xavier for 6th straight win
Phil Booth scored 22 points, Collin Gillespie added 18 and No. 22 Villanova beat Xavier 85-75 on Friday night for its sixth straight win.