Texas Southern (1-13) won its first game of the season in a Southwestern Athletic Conference opener for both teams.
Bruce made a career-best eight 3s on 12 attempts and Jefferson was 5 of 11 as Texas Southern made 15 of 38 from 3-point range. Jefferson reached 20-plus points for the 10th time this season.
Texas Southern went on a 17-5 run -- with three 3-pointers from Bruce -- midway through the first half for a 27-13 lead. But Southern closed the half by scoring the final six points to pull within 37-34.
Southern was within 52-48 with 13:37 to go but didn't make its next field goal until the 8:21 mark and trailed 66-51.
Jim Calhoun, who has a career record of 873-380 and led UConn to three national titles before retiring in 2012, has been hired as coach at Saint Joseph.
Pac-12 commissioner Larry Scott believes a tentative ruling making show-cause orders illegal in California would threaten NCAA membership for state schools.
Guard James Bouknight, ranked 87th in the ESPN 100, is the first player from the Class of 2019 to commit to UConn and first-year coach Dan Hurley.