Bethune-Cookman (10-9) won its fifth straight to match its win total from last season.
Bethune-Cookman opened the game with a 17-7 spurt and led 34-24 after Tabb closed the half with a 3-pointer. The Wildcats extended their lead to 17 points following an 11-0 run but Stetson answered by scoring the next 10 points -- with eight coming from the free-throw line.
Stetson's Leo Goodman stepped into a 3-pointer with 7:06 remaining to cut it to 56-50, but Bethune-Cookman went on a 16-4 run -- with five points apiece from Shawntrez Davis and Isaiah Bailey -- to make it 72-54.
Davis and Bailey added 17 points apiece for Bethune-Cookman.
Volusia County's only two Division I programs first met in 1967 and have played each other at least one every year since 2010.
Vanderbilt upsets No. 18 Arizona State
The Commodores hit 12 from beyond the arc to earn an 81-65 victory against the Sun Devils.
Picking a winner in Duke freshmen vs. the Fab Five
When it comes to the hypothetical matchup between historic freshman classes, Las Vegas and Jalen Rose don't see eye to eye.
Giant Killers: Has Buffalo turned into a Giant?
The Bulls shocked Arizona in last year's tournament, but another surprise seems unlikely. They're 10-0 heading into Tuesday's game at Syracuse.