| Date | GMT/BST | Home | Away | HT | Attend. | |||
|---|---|---|---|---|---|---|---|---|
| March 2012 | ||||||||
| Sun 11 | 23:00 | Chivas USA | 0-1 | Houston | 0-0 | 14,464 | Report | |
| Sat 17 | 21:00 | San Jose | 0-1 | Houston | 0-1 | 21,816 | Report | |
| Sat 24 | 02:00 | Seattle Sounders FC | 2-0 | Houston | 2-0 | 38,304 | Report | |
| April 2012 | ||||||||
| Sun 15 | 00:00 | Chicago | 1-1 | Houston | 1-1 | 10,489 | Eastern Conf | Report |
| Sat 21 | 00:30 | Columbus | 2-2 | Houston | 0-0 | 10,479 | Eastern Conf | Report |
| Sat 28 | 00:30 | DC United | 3-2 | Houston | 1-0 | 13,975 | Eastern Conf | Report |
| May 2012 | ||||||||
| Wed 9 | 00:00 | New York Red Bulls | 1-0 | Houston | 1-0 | 11,315 | Eastern Conf | Report |
| Sat 12 | 21:30 | Houston | 1-0 | DC United | 0-0 | 22,039 | Eastern Conf | Report |
| Wed 16 | 01:30 | Houston | 0-0 | Portland Timbers | 0-0 | 22,039 | Report | |
| Sat 19 | 00:30 | New England | 2-2 | Houston | 1-1 | 16,414 | Eastern Conf | Report |
| Sat 26 | 19:30 | Houston | 2-1 | Los Angeles | 1-1 | 22,039 | Report | |
| June 2012 | ||||||||
| Sun 10 | 00:00 | Vancouver Whitecaps | 3-1 | Houston | 1-0 | 18,811 | Report | |
| Sat 16 | 00:30 | Houston | 2-1 | FC Dallas | 1-0 | 22,039 | Report | |
| Wed 20 | 02:00 | Houston | 3-3 | Toronto FC | 1-3 | 21,423 | Eastern Conf | Report |
| Sat 23 | 00:30 | Montreal Impact | 4-2 | Houston | 2-2 | 12,357 | Eastern Conf | Report |
| July 2012 | ||||||||
| Tue 3 | 01:30 | Houston | 0-0 | Chicago | 0-0 | 22,039 | Eastern Conf | Report |
| Sun 8 | 01:00 | Kansas City | 0-0 | Houston | 0-0 | 19,307 | Eastern Conf | Report |
| Sun 15 | 02:00 | Houston | 4-0 | DC United | 2-0 | 18,871 | Eastern Conf | Report |
| Wed 18 | 01:30 | Houston | 2-1 | Kansas City | 1-1 | 19,761 | Eastern Conf | Report |
| Sat 21 | 01:30 | Houston | 3-0 | Montreal Impact | 1-0 | 20,396 | Eastern Conf | Report |
| Sat 28 | 21:30 | Toronto FC | 0-2 | Houston | 0-0 | 19,652 | Eastern Conf | Report |
| August 2012 | ||||||||
| Fri 3 | 01:00 | Houston | 2-0 | New York Red Bulls | 2-0 | 22,039 | Eastern Conf | Report |
| Sat 11 | 01:00 | New York Red Bulls | 2-0 | Houston | 0-0 | 15,730 | Eastern Conf | Report |
| Sun 19 | 02:00 | Houston | 2-2 | Columbus | 1-1 | 20,567 | Eastern Conf | Report |
| Sat 25 | 01:30 | Houston | 1-1 | Toronto FC | 1-0 | 19,320 | Eastern Conf | Report |
| September 2012 | ||||||||
| Sun 2 | 00:00 | Chicago | 3-1 | Houston | 2-0 | 17,007 | Eastern Conf | Report |
| Thu 6 | 01:30 | Houston | 1-0 | Real Salt Lake | 0-0 | 18,452 | Report | |
| Sat 15 | 01:30 | Kansas City | 1-1 | Houston | 0-0 | 19,877 | Eastern Conf | Report |
| Sun 23 | 21:00 | Philadelphia Union | 3-1 | Houston | 1-1 | 17,666 | Eastern Conf | Report |
| Sat 29 | 01:30 | Houston | 2-0 | New England | 0-0 | 22,039 | Eastern Conf | Report |
| October 2012 | ||||||||
| Sat 6 | 01:30 | Houston | 1-1 | Montreal Impact | 1-0 | 21,733 | Eastern Conf | Report |
| Sat 20 | 00:30 | Houston | 3-1 | Philadelphia Union | 1-1 | 22,039 | Eastern Conf | Report |
| Sat 27 | 01:00 | Colorado | 2-0 | Houston | 1-0 | 15,453 | Report | |
| Wed 31 | 01:00 | Chicago | 1-2 | Houston | 0-1 | 10,923 | Eastern Knockout | Report |
| November 2012 | ||||||||
| Sun 4 | 20:30 | Houston | 2-0 | Kansas City | 1-0 | 20,689 | East Semi | Report |
| Thu 8 | 02:00 | Kansas City | 1-0 | Houston | 0-0 | East Semi L2 | Report | |
| Sun 11 | 21:00 | Houston | 3-1 | DC United | 0-1 | 22,101 | Eastern Final | Report |
| Sun 18 | 21:00 | DC United | 1-1 | Houston | 0-1 | 20,015 | Eastern Final L2 | Report |
| December 2012 | ||||||||
| Sat 1 | 21:55 | Los Angeles | 3-1 | Houston | 0-1 | 30,510 | Final | Report |
