| Date | BST/GMT | Home | Away | HT | Attend. | ||
|---|---|---|---|---|---|---|---|
| August 2012 | |||||||
| Sun 26 | 19:45 | Siena | 0-0 | Torino | 0-0 | 8,251 | Report |
| September 2012 | |||||||
| Sun 2 | 19:45 | Sampdoria | 2-1 | Siena | 1-0 | 22,587 | Report |
| Sun 16 | 14:00 | Siena | 2-2 | Udinese | 0-2 | 7,831 | Report |
| Sun 23 | 14:00 | Internazionale | 0-2 | Siena | 0-0 | 40,357 | Report |
| Thu 27 | 19:45 | Siena | 1-0 | Bologna | 0-0 | 8,180 | Report |
| Sun 30 | 14:00 | Lazio | 2-1 | Siena | 2-0 | 28,512 | Report |
| October 2012 | |||||||
| Sun 7 | 14:00 | Siena | 1-2 | Juventus | 1-1 | 15,373 | Report |
| Sun 21 | 14:00 | Atalanta | 2-1 | Siena | 0-0 | 18,344 | Report |
| Sat 27 | 17:00 | Siena | 0-0 | Palermo | 0-0 | 8,708 | Report |
| Wed 31 | 19:45 | Cagliari | 4-2 | Siena | 3-1 | 4,389 | Report |
| November 2012 | |||||||
| Sun 4 | 14:00 | Siena | 1-0 | Genoa | 0-0 | 8,076 | Report |
| Sun 11 | 14:00 | Parma | 0-0 | Siena | 0-0 | 10,611 | Report |
| Sun 18 | 14:00 | Siena | 1-0 | US Pescara | 1-0 | 8,382 | Report |
| Sun 25 | 14:00 | Chievo Verona | 0-0 | Siena | 0-0 | 6,000 | Report |
| December 2012 | |||||||
| Sun 2 | 14:00 | Siena | 1-3 | AS Roma | 1-0 | 10,291 | Report |
| Sun 9 | 14:00 | Siena | 1-3 | Catania | 1-0 | 8,240 | Report |
| Sun 16 | 11:30 | Fiorentina | 4-1 | Siena | 3-0 | 22,455 | Report |
| Sat 22 | 14:00 | Siena | 0-2 | Napoli | 0-0 | 9,489 | Report |
| January 2013 | |||||||
| Sun 6 | 14:00 | AC Milan | 2-1 | Siena | 0-0 | 30,404 | Report |
| Sun 13 | 11:30 | Torino | 3-2 | Siena | 3-1 | 10,783 | Report |
| Sun 20 | 14:00 | Siena | 1-0 | Sampdoria | 0-0 | 7,961 | Report |
| Sun 27 | 14:00 | Udinese | 1-0 | Siena | 1-0 | 11,011 | Report |
| February 2013 | |||||||
| Sun 3 | 14:00 | Siena | 3-1 | Internazionale | 2-1 | 12,130 | Report |
| Sun 10 | 14:00 | Bologna | 1-1 | Siena | 1-1 | 20,968 | Report |
| Mon 18 | 19:45 | Siena | 3-0 | Lazio | 2-0 | 8,679 | Report |
| Sun 24 | 14:00 | Juventus | 3-0 | Siena | 1-0 | 38,461 | Report |
| March 2013 | |||||||
| Sun 3 | 14:00 | Siena | 0-2 | Atalanta | 0-1 | 8,155 | Report |
| Sun 10 | 14:00 | Palermo | 1-2 | Siena | 1-0 | 18,214 | Report |
| Sun 17 | 11:30 | Siena | 0-0 | Cagliari | 0-0 | 8,639 | Report |
| Sat 30 | 14:00 | Genoa | 2-2 | Siena | 1-1 | Report | |
| April 2013 | |||||||
| Sun 7 | 14:00 | Siena | 0-0 | Parma | 0-0 | 9,000 | Report |
| Sat 13 | 17:00 | US Pescara | 2-3 | Siena | 0-2 | Report | |
| Sun 21 | 14:00 | Siena | 0-1 | Chievo Verona | 0-1 | 9,500 | Report |
| Sun 28 | 14:00 | AS Roma | 4-0 | Siena | 3-0 | 41,949 | Report |
| May 2013 | |||||||
| Sun 5 | 14:00 | Catania | 3-0 | Siena | 1-0 | Report | |
| Wed 8 | 19:45 | Siena | 0-1 | Fiorentina | 0-1 | 9,000 | Report |
| Sun 12 | 14:00 | Napoli | 2-1 | Siena | 0-1 | 52,433 | Report |
| Sun 19 | 19:45 | Siena | 1-2 | AC Milan | 1-0 | 9,500 | Report |