Guardado has been a vital part of Mexico's national team under Juan Carlos Osorio, who is also facing fitness doubts over Hector Moreno.
2017 SeasonAll times ET
Saul Niguez was denied by the crossbar as second-placed Atletico Madrid were held to a 0-0 La Liga draw by Real Betis.
Borussia Dortmund fans gave Marc Bartra an emotional farewell before Thursday's UEFA Europa League tie against Salzburg in the round of 16.
Scouting Spotlight profiles Elseid Hysaj, Jordan Torunarigha and Fabian Ruiz with the trio's performances catching clubs' eyes across Europe.
Marco Asensio scored twice as Real Madrid pulled off an exciting second-half comeback to beat Real Betis 5-3 on Sunday night in Seville.
Clarence Seedorf's first game in charge of Deportivo La Coruna ended in a 1-0 La Liga home defeat to Real Betis.
Sporting Kansas City completed the signing of Chile midfielder Felipe Gutierrez as a designated player on Tuesday.
Marc Bartra said an emotional farewell to Borussia Dortmund after signing for Real Betis on a five-and-a-half-year contract.
Barcelona opened up an 11-point lead at the top of LaLiga after hammering Real Betis 5-0 at the Estadio Benito Villamarin on Sunday.
West Ham manager David Moyes is due to travel to watch Real Betis midfielder Fabian Ruiz play against Barcelona, sources have told ESPN FC.
Former Real Betis and Napoli goalkeeper Toni Doblas is set to join Philippines Football League (PFL) champions Ceres-Negros for the 2018 season.
Fernando Torres' first goal in La Liga this season gave Atletico Madrid a hard-fought 1-0 win over Alaves on Saturday and lifted the club into second.
Saul Niguez scored the only goal as Atletico Madrid beat Real Betis 1-0 to keep Diego Simeone's team in the chase for the La Liga title.
"I understand football through the ball." Speaking exclusively to ESPN FC, Real Betis coach Quique Setien explains his philosophy about the sport.
Jack Wilshere was thought to be staying in the Premier League, but reports suggest he could move to Spain. As always, Transfer Talk has the latest.
Real Betis scored twice in the final 22 minutes to salvage a 2-2 LaLiga draw at home to Getafe on Friday night.
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