The Panthers (5-2, 3-1 Conference USA) are off to their best start in school history. It was also their second straight win against the Thundering Herd and their first at Marshall (6-2, 3-1).
McGough was 14-of-18 passing, and Owens finished with seven catches for 114 yards. They capped back-to-back scoring drives late in the second half.
Napoleon Maxwell ran for 93 yards and a touchdown, and Alex Gardner added another 71 yards rushing and a score. Brad Muhammad's 12-yard interception return for a touchdown stretched the Panthers' lead to 35-7 midway through the third quarter.
Chase Litton threw for 363 yards and three touchdowns, including two TD passes in the fourth quarter for Marshall.
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Happy with how Tua Tagovailoa and Jalen Hurts have handled split quarterback duties this season, Alabama coach Nick Saban told ESPN's Chris Low on Thursday that he plans to use both players for the remainder of the season.
Baker Mayfield pulls off a trick play, where he catches a 2-point conversion, similar to a play he executed for a touchdown in the 2018 Rose Bowl.
Ryquell Armstead ran for 108 yards and a touchdown, the Temple defense scored on two of its five turnovers and the Owls beat Tulsa 31-17 on Thursday night in an American Athletic Conference opener for both teams.
Tulsa QB Luke Skipper is stripped from behind by Temple's Sam Franklin and teammate Chapelle Russell recovers it to seal the win.
Tulsa's Corey Taylor II runs in a five-yard touchdown to shrink Tulsa's deficit to 28-17.
Down 28-10 early in the fourth, Cooper Edmiston intercepts Temple QB Anthony Russo to begin a Tulsa scoring drive.