McGuire, who had just 41 yards in the first half, now has 13 games with 100 or more yards rushing. Jennings was 15-of-21 passing and Ja'Marcus Bradley grabbed six for 97 yards.
Louisiana-Lafayette (1-1) was up 14-12 at the break. The Cowboys took their only lead when Trent Manuel nailed a 28-yard field goal with 9:31 left in the third quarter. The Ragin' Cajuns responded quickly, retaking the lead for good on Raymond Calais' rushing score from the seven with 7:18 left.
McNeese State (1-1) closed to within eight when Dylan Long plunged in from the three with 12 seconds left. The ensuing onside kick failed.
James Tabary threw for 237 yards for McNeese State.
Heupel: UCF has elite players at skill positions
UCF head coach Josh Heupel speaks with SVP about the Knights' continued success and a primetime game vs. Cincinnati.
Contenders for SEC Coach of the Year
The Thinking Out Loud crew makes their picks on who would be their coach of the year from the conference.
Guarantano continuing to progress
Thinking Out Loud's Greg McElroy and Marcus Spears discuss how Tennessee continues to improve on offense and defense.
Williams: 'This is a unit, a family'
Texas A&M RB Trayveon Williams joins Thinking Out Loud to discuss how the Aggies have bounced back after two tough losses.
David Montgomery, Greg Roberts each missing first half of their teams' games Saturday
After a scuffle led to their ejections this past Saturday, Iowa State running back David Montgomery and Baylor defensive end Greg Roberts will miss the first half of their team's games this week -- vs. Texas and vs. TCU, respectively.
Louisville interim coach says final 2 games about players, not permanent position
Louisville interim football coach Lorenzo Ward said he is focused solely on salvaging the Cardinals' final two games rather than whether he will have the job permanently.