Follow all the action as Mauricio Pochettino returns to St Mary's with both sides battling for European football.
Jose Mourinho has hit back at Arsenal boss Arsene Wenger as he defended his team's tactics ahead of their trip to Emirates Stadium on Sunday.
Sources have confirmed that Ilkay Gundogan has informed Borussia Dortmund that he wants to leave the club in the summer.
Arsene Wenger says he has "no big regrets" over Arsenal's failure to sign Eden Hazard before his switch to Chelsea, saying: "It was not feasible."
Formula One world champion tops list for second year in a row, while former McLaren team-mate Jenson Button drops to third behind England captain Wayne Rooney.
Southampton manager Ronald Koeman says he'd stay with his Saints team next season even if Barcelona or Real Madrid came calling.
Six-time Olympic champion Usain Bolt describes rival Tyson Gay's reduced punishment as "the stupidest thing I've ever heard."
Tickets already being offered on secondary seller websites after official outlets sell out within minutes on Thursday.
AP McCoy has always been in awe of Lionel Messi, Paul Scholes and Lester Piggott. With retirement awaiting, Ian Chadband explains why the greatest sportsman of our era is a hero of humility.
Manchester United manager Louis van Gaal said he would not discuss reports that PSV Eindhoven winger Memphis Depay had travelled to Manchester.
Louis van Gaal has admitted he is worried that David de Gea's delay in signing a new contract means he's likely to reject it.
The Prime Minister of the United Kingdom gets his claret and blues mixed up while speaking at a political event in Croydon.
Steven Gerrard and Frank Lampard will be honoured for their contributions to English football by the Professional Footballers' Association at the week
West Indies respond strongly on fourth day of second Test as England's hopes of victory fade.
Defending champion Alexander Levy faltered late after a strong third-round start Saturday, falling into a four-way tie for the lead at the Volvo China Open.
Manchester City boss Manuel Pellegrini has played down talk that City will sell midfielder Samir Nasri, who failed to replicate his form last season.
Having failed to beat Jose Mourinho on 12 previous occasions, Arsene Wenger can end a personal hoodoo on Sunday. A victory for Arsenal over Chelsea would also lay down a marker for next season, writes James Dall.
Badou Jack outpointed Anthony Dirrell to take the WBC super-middleweight title and Danny Jacobs defended his WBA middleweight title by stopping Caleb Truax on Friday night at the UIC Pavilion.
Mark Selby suffered a shock second-round defeat exit at the World Championship after qualifier Anthony McGill secured a 13-9 victory at the Crucible.
British running icon Paula Radcliffe tells Simon Barnes about her career highs and lows and her passion for fighting drug cheats as she prepares for a London Marathon celebration.
Everton midfielder Ross Barkley is "too young" to move to Manchester City at the end of this season, according to teammate Gareth Barry.
Defending champion Kei Nishikori made his way into the semifinals of the Barcelona Open by holding off Roberto Bautista Agut 6-2, 3-6, 6-1 on Friday.
Cross-code star surprised at Man of the Match award after scoring try in Bath's Aviva Premiership victory over London Irish.
Hudson Swafford didn't want to dwell on the pressure of the high-stakes weekend that awaits him.
The ESPN FC panel discuss the upcoming Premier League match between Chelsea and Arsenal, and note Arsenal's lack of results against the Blues as a troubling statistic.
Simona Halep of Romania and Caroline Wozniacki of Denmark will meet in the semifinals of the Porsche Grand Prix after winning their respective quarterfinals on Friday.
Who has the advantage in the May 2 Floyd Mayweather-Manny Pacquiao superfight? Let's ask the five men who have shared the ring with both fighters.
Mauricio Pochettino has denied speculation that Hugo Lloris is considering his future at Tottenham.
Judd Trump is safely through to the second round of the World Championship after holding off a fightback from qualifier Stuart Carrington to secure a 10-6 victory at the Crucible.
Tiger Woods has announced that he will compete in the upcoming Players Championship, the PGA Tour's flagship event which he won two years ago and missed due to injury last year.
Sunderland winger Adam Johnson appears set to remain available for selection after being charged with three offences of sexual activity with a child.
Tottenham Hotspur are open to prospect of their new White Hart Lane stadium being used to host events other than soccer, sources told ESPN FC.
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Pelle has scored twice in his last three Premier League appearances after failing to find the back of the net in the league since December.
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Southampton take a 1-0 lead against Tottenham, and it's Pelle on the scoresheet. Calamitous defending allows the Italian to poke home.
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Chance! Schneiderlin clips a shot at the near post but Lloris is down smartly to parry the ball around the post.